AOD Acetate Nasal Spray

$51.00

(AOD-9604 Acetate 5  mg – 42 mcg) is a synthetic 15-amino-acid peptide made from the C-terminal region (177-192) of human growth hormone (hGH), with a slight modification to an N-terminal tyrosine, to help keep the compound stable. It was originally developed to study how fat metabolism works, without triggering the full effects of growth hormone.

In research settings, AOD-Acetate is studied for: 

  • Fat Metabolism Signalling: Researchers are examining how AOD-9604 may influence fat-related signalling pathways without activating the full growth hormone signalling cascade.
  • Adipocyte Activity & Lipolysis: In preclinical models, AOD acetate has been investigated for its interaction with fat cells, including how it breaks down, and its possible effects on reducing fat storage.
  • Insulin Sensitivity: Unlike the full-length human growth hormone, AOD-9604 acetate has been studied for its weight loss effects without negatively impacting insulin activity in animal models.

Our 15 mL research solution contains 5 mg total AOD-9604 acetate, prepared in a nasal spray format for experimental applications. Each bottle delivers approximately 120 sprays, for controlled, repeatable measurements for research workflows.

Restricted Research Purchase
Purchases are limited to qualified research customers with a verified account. 

⚠️ Notice: This product is for research use only and intended solely for laboratory testing. It is not for human or animal use. Only qualified professionals should handle it. This product is not a drug, food, or cosmetic.

What is AOD-9604 Acetate?

AOD-9604 is a peptide fragment modeled after the fat-related region of human growth hormone, designed to retain metabolic signaling activity without the growth-promoting effects of full-length hGH.

The “acetate” designation simply means that the peptide is supplied as a stable salt form, making it easier to work with and store. It doesn’t mean that the AOD peptide itself is chemically modified.

AOD-9604 Peptide Chemical Information

Sequence: Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe
Molecular formula: C33H54N12O15
Molecular weight: ~1875.1 g/mol
Form: Synthetic peptide, nasal spray research solution
Other Ingredients: Lab-Grade Distilled Water.

Each batch of our AOD-Acetate nasal spray is produced using high-purity synthetic peptide material and undergoes internal and third-party lab analysis to verify: 

  • Identify (peptide sequencing verification)
  • Purity (≥99% by HPLC)
  • Absence of contaminants (microbial, heavy metals, solvents)

All materials are supplied strictly for research and laboratory use only. 

Research Related to AOD-9604 Peptide

AOD-9604 has been studied primarily in in vitro and animal models, where it’s been explored for its role in fat metabolism signaling without the anabolic or growth-promoting effects associated with growth hormone.

Animal Obesity

AOD-9604 is a small piece of human growth hormone that focuses on fat metabolism. In studies with overweight mice, intravenous administration of AOD-9604 reduced body fat and body weight by promoting the breakdown of stored fat and its use for energy. 

Because this hGH fragment doesn’t induce the full effects of growth hormone, AOD-9604 has fewer side effects, making it an ideal compound to study in relation to fat and metabolism [1].

Tissue Repair

Researchers used New Zealand White rabbits to develop a controlled model of knee joint damage that mimics osteoarthritis. They wanted to compare the results of saline, hyaluronic acid, AOD-9604, and a combination of AOD-9604 with hyaluronic acid. [2]

Regeneration Research

After several weeks, the combination group showed the least cartilage damage and recovered from lameness the fastest, while the saline group showed the most joint degeneration. These findings suggest that AOD-9604 may support cartilage repair mechanisms in animal studies, particularly when studied alongside hyaluronic acid, indicating the potential of the AOD peptide to aid tissue repair and regeneration [2].

Sources

  1. Ng, F. M., Sun, J., Sharma, L., Libinaka, R., Jiang, W. J., & Gianello, R. (2000). Metabolic studies of a synthetic lipolytic domain (AOD9604) of human growth hormone. Hormone research, 53(6), 274-278.
  2. Kwon, D. R., & Park, G. Y. (2015). Effect of intra-articular injection of AOD9604 with or without hyaluronic acid in rabbit osteoarthritis model. Annals of Clinical & Laboratory Science, 45(4), 426-432.

Frequently asked questions

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What does “For Research Use Only” mean?

All products on Stemcode are intended strictly for laboratory, academic, and scientific research purposes. They are not approved for human or veterinary use.

Due to the sensitive nature of research materials used, all sales are final unless the product arrives damaged or incorrect.

No. Resale or repackaging without authorization is prohibited. Our products are solely for research.

At this moment, we ship only within the United States.

Each product page includes specific storage guidelines (e.g., refrigeration or room temperature).