Nasal Spray
MOTS-C Nasal Spray
Mitochondrial-derived peptide nasal spray, 20mg total, 80 sprays at 250mcg per spray.
Est. delivery
Certificate of Analysis
Reference Chemistry
Chemical Specification
- CAS #
- 1627580-64-6
- Molecular Formula
- M.W.
- 2174.6 g/mol
Reference chemistry verified against PubChem. HPLC purity is the most recent reported value from an on-file COA for this product.
RESEARCH USE ONLY — not for human or animal consumption. Not for diagnostic or therapeutic use.
Key Ingredients
A mitochondrial-derived peptide that activates the AMPK pathway. Research documents effects on glucose metabolism, insulin sensitivity, and exercise capacity in pre-clinical models.
Discover the researchDescription
MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA Type-c) is a 16-amino-acid mitochondrial-derived peptide encoded within the 12S rRNA gene of mitochondrial DNA. It is one of several mitochondrial-derived peptides (MDPs) that play roles in metabolic regulation.
Research Background
MOTS-c has been described as an exercise mimetic in preclinical research. Studies have demonstrated its ability to activate AMPK, regulate the folate-methionine cycle, and improve insulin sensitivity. Research suggests it translocates to the nucleus under metabolic stress to regulate adaptive gene expression. For research use only.
Ingredients & Dosage
| MOTS-c | 250 mcg per spray |
Inactive ingredients / formulation base
| Normal Saline (pH 6.0) | Base solution |
| Benzalkonium Chloride (BKC) | 0.01% preservative |
| Lab-Grade Distilled Water | QS |
SKU: MON0020MG
Shipping & Storage
Shipping: Every order ships 2-Day — free on orders $150+, $4.99 otherwise. Orders placed before 3 PM PT on a business day dispatch the same day, and delivery is typically 2 business days after dispatch.
Storage: Store in a cool, dry place. Refrigeration recommended after opening for optimal stability. Keep away from direct sunlight.
Regulatory Statement
For laboratory and research use only. Not for human or animal consumption. This product is sold exclusively to qualified researchers and licensed laboratories.
This product is not a drug, food, or cosmetic, and is not for diagnostic or therapeutic use. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
A certificate of analysis (COA) is available for this product — view the published COA.
Mitochondrial-Derived Peptide
Mitochondrial-derived peptide for metabolic regulation studies
MOTS-c is a 16-amino acid peptide encoded within the mitochondrial 12S rRNA gene. Discovered by Dr. Changhan Lee at USC, it has been studied for its role in metabolic homeostasis and exercise physiology.
Published Research Data
Quantified findings from peer-reviewed studies on MOTS-c
Published Research
Studies on MOTS-c
2021 MOTS-c is an exercise-induced mitochondrial-encoded regulator of age-dependent physical decline and muscle homeostasis Nat Commun
2015 The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance Cell Metab
Discovery paper identifying MOTS-c as a mitochondrial-derived peptide that regulates metabolic homeostasis through AMPK pathway activation.
Why Research Peptides
All comparisons reflect general industry practices. Stemcode products are intended solely for laboratory research and are not for human consumption.
The Research Standard
All comparisons reflect general industry practices. Stemcode products are intended solely for laboratory research and are not for human consumption.
