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Documented in Peer-Reviewed Research

AHK-Cu + GHK-Cu

Copper Peptide Complex

GHK-Cu and AHK-Cu represent two distinct copper peptide sequences with complementary mechanisms of action. Published research documents their roles in extracellular matrix regulation, fibroblast activity, and growth factor expression.

  • Collagen I & III Synthesis
  • ECM Remodeling
  • VEGF Upregulation
  • Gene Expression Modulation

Quantified findings reported in the literature

4,000+

human genes modulated by GHK-Cu in gene expression analysis

Pickart & Margolina, IJMS 2018

70%

increase in collagen synthesis observed in fibroblast cultures treated with GHK-Cu

Pickart et al., BioMed Res Int 2015

300%

increase in VEGF expression in dermal papilla cells exposed to AHK-Cu

Pyo et al., Arch Pharm Res 2007

47%

reduction in TNF-alpha inflammatory markers in GHK-Cu treated tissue models

Pickart & Margolina, IJMS 2018

96-99%

HPLC-verified purity range across published Certificates of Analysis

Stemcode Peptides COA data

32

collagen and ECM-related genes upregulated by GHK-Cu in connectivity map data

Pickart et al., BioMed Res Int 2015

Published, peer-reviewed studies

  1. Int J Mol Sci2018

    Regenerative and protective actions of the GHK-Cu peptide in the light of new gene data

    View source on PubMed/DOI ↗
  2. BioMed Res Int2015

    GHK peptide as a natural modulator of multiple cellular pathways in skin regeneration

    View source on PubMed/DOI ↗
  3. Arch Pharm Res2007

    The effect of tripeptide-copper complex on human hair growth in vitro

    View source on PubMed/DOI ↗
  4. Cosmetics2012

    GHK-Cu may prevent oxidative stress in skin by regulating copper and modifying expression of numerous antioxidant genes

    View source on PubMed/DOI ↗
  5. J Pept Sci2008

    The human tri-peptide GHK and tissue remodeling

    View source on PubMed/DOI ↗

Stemcode supplies AHK-Cu + GHK-Cu as a research-grade compound for laboratory research use only — not for human or animal consumption.

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Every compound is documented in published, peer-reviewed literature. Our research library indexes 43 studies across 35 journals for 20 compounds.

Our Studies →
43

Peer-reviewed studies in our research library have examined the mechanisms of action of these peptide compounds.

20
Peptide Compounds
35
Journals Referenced
43
Published Studies

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