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Documented in Peer-Reviewed Research

SS-31

Mitochondria-Targeted Peptide

SS-31 (Elamipretide) is a synthetic tetrapeptide that selectively concentrates in the inner mitochondrial membrane. It binds to cardiolipin, stabilizing electron transport chain complexes and reducing mitochondrial reactive oxygen species.

  • Cardiolipin Binding
  • ETC Stabilization
  • ROS Reduction
  • Mitochondrial Targeting

Quantified findings reported in the literature

4

amino acid residues in the SS-31 tetrapeptide sequence

Szeto, AAPS J 2006

1,000x

concentration enrichment of SS-31 in mitochondria vs cytoplasm

Zhao et al., Cell Death Dis 2004

96-99%

HPLC-verified purity range across published batch testing

Stemcode Peptides COA data

Published, peer-reviewed studies

  1. AAPS J2006

    Cell-permeable, mitochondrial-targeted, peptide antioxidants

    Characterization of SS-31's selective targeting of the inner mitochondrial membrane and cardiolipin-dependent mechanisms of action.

    View source on PubMed/DOI ↗
  2. J Am Soc Nephrol2014

    Mitochondria-targeted peptide accelerates ATP recovery and reduces ischemic kidney injury

    View source on PubMed/DOI ↗

Third-party analytical reports

Certificates of Analysis from independent laboratories for products supplied by Stemcode. Reported values describe the analysed material; they are reported as documented and are distinct from the published literature above.

SS-31Freedom Diagnostics
Purity (HPLC)
99.830%
Net content
2.82 mg/mL
Lot
SP26-SSN30
COA #
2604100417
Report date
04/12/2026
View full report ↗

Stemcode supplies SS-31 as a research-grade compound for laboratory research use only — not for human or animal consumption.

View the research-grade product →

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Every compound is documented in published, peer-reviewed literature. Our research library indexes 43 studies across 35 journals for 20 compounds.

Our Studies →
43

Peer-reviewed studies in our research library have examined the mechanisms of action of these peptide compounds.

20
Peptide Compounds
35
Journals Referenced
43
Published Studies

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