epitalon-chemical-information

Epitalon Tablets

$89.00

Epitalon , also called Epithalon,  is a synthetic tetrapeptide developed to mimic the natural peptide Epithalamin found in the pineal gland. It’s studied primarily on its effects on telomeres — the protective caps at the ends of DNA. As cells divide, telomeres get shorter, leading to cellular aging or shutdown. Scientists study Epitalon to understand how cell traits and functions are controlled.

Other areas of research in which Epitalon is studied include:

  • Antioxidant Activity: Research suggests that epitalon may reduce oxidative stress and support healthy cell function.
  • Circadian Rhythm: Epitalon is explored for its possible role in regulating healthy sleep-wake cycles and melatonin production.
  • Longevity Studies: Its effects on telomeres make it an interesting peptide for its potential on lifespan and other markers of healthy aging.
  • Cell Protection: Epitalon is looked at for its role in supporting DNA stability and cellular repair.

Our Epitalon tablets contain 3mg total Epitalon peptide, prepared in 45 tablets with a total of 135 mg per bottle, allowing for precise measurements.

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⚠️ Notice: This product is for research use only and intended solely for laboratory testing. It is not for human or animal use. Only qualified professionals should handle it. This product is not a drug, food, or cosmetic.

What is Epitalon?

Epithalon or Epitalon is a synthetic peptide made up of four amino acids. It was developed to mimic the actions of a natural peptide called epithalamin, produced in the pineal gland. Scientists became interested in Epitalon peptide because of its possible influence on healthy cell aging, telomere maintenance, and gene regulation. Because Epitalon is a small molecule, with new developments, scientists have found a way to make Epitalon more stable in tablet format, making it easier to administer over injectables.

Epitalon Chemical Information

Sequence: Ala-Glu-Asp-Gly Molecular formula: C₁₄H₂₂N₄O₉ Molecular weight: ~390.3 g/mol Form: Synthetic peptide, tablets Other Ingredients: Magnesium Stearate, Microcrystalline Cellulose, Dicalcium Phosphate, Silicon Dioxide

Epitalon Lab Testing & Purity

Our Epitalon is produced with high-purity peptide material and undergoes in-house and third-party lab analysis to confirm:

  • Identify (peptide sequencing verification)
  • Purity (≥99% by HPLC)
  • Absence of contaminants (microbial, heavy metals, solvents)

Lab testing ensures that the material provided is consistent, high-quality, and suitable for research purposes.

Research Related to Epitalon

Here are some highlighted areas of research related to the Epithalon peptide. Please note that Epitalon is not approved as a dietary supplement or a drug. Its use remains restricted to laboratory research only.

Telomere Support

Research shows that Epitalon may work by turning on telomerase, an enzyme that helps rebuild and maintain telomeres, which are the protective caps at the ends of DNA strands. Telomeres get shorter each time a cell divides, which eventually causes the cell to age and stop working. By activating telomerase, Epitalon may slow down this shortening process, allowing cells to keep functioning longer. In animal studies, this effect was linked with healthier cells and a longer lifespan [12]

Cellular Regeneration & Repair

Epitalon may promote DNA repair, leading to improved cell proliferation and function. It may also reduce errors in chromosomes and strengthen the body’s antioxidant defenses, which protect cells from damage. Together, these effects are thought to support tissue repair and overall cellular health [3].

Hormonal Health

Epitalon may support hormonal balance by influencing the pineal gland, which also regulates melatonin production and the body’s circadian rhythm. In aging animals, Epitalon restored healthy melatonin secretion to more youthful levels, which helped improve the sleep-wake cycle and overall endocrine function. Some studies also found that it helped balance gonadotropins — luteinizing hormone and follicle-stimulating hormones — through its effects on the hypothalamic-pituitary axis [1, 3, 4].

Sources

  1. Khavinson, V. K., Bondarev, I. E., & Butyugov, A. A. (2003). Epithalon peptide induces telomerase activity and telomere elongation in human somatic cells. Bulletin of Experimental Biology and Medicine, 135(6), 590-592.
  2. Khavinson, V., Diomede, F., Mironova, E., Linkova, N., Trofimova, S., Trubiani, O., … & Sinjari, B. (2020). AEDG peptide (Epitalon) stimulates gene expression and protein synthesis during neurogenesis: possible epigenetic mechanism. Molecules, 25(3), 609.
  3. Araj, S. K., Brzezik, J., Mądra-Gackowska, K., & Szeleszczuk, Ł. (2025). Overview of Epitalon—Highly Bioactive Pineal Tetrapeptide with Promising Properties. International Journal of Molecular Sciences, 26(6), 2691.
  4. Goncharova, N. D., Vengerin, A. A., Khavinson, V. K., & Lapin, B. A. (2005). Pineal peptides restore the age-related disturbances in hormonal functions of the pineal gland and the pancreas. Experimental gerontology, 40(1-2), 51-57.

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What does “For Research Use Only” mean?

All products on Stemcode are intended strictly for laboratory, academic, and scientific research purposes. They are not approved for human or veterinary use.

Due to the sensitive nature of research materials used, all sales are final unless the product arrives damaged or incorrect.

No. Resale or repackaging without authorization is prohibited. Our products are solely for research.

At this moment, we ship only within the United States.

Each product page includes specific storage guidelines (e.g., refrigeration or room temperature).

Description

Epitalon , also called Epithalon,  is a synthetic tetrapeptide developed to mimic the natural peptide Epithalamin found in the pineal gland. It’s studied primarily on its effects on telomeres — the protective caps at the ends of DNA. As cells divide, telomeres get shorter, leading to cellular aging or shutdown. Scientists study Epitalon to understand how cell traits and functions are controlled.

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