tesamorelin dna and formula structure
  • Nasal Spray

Tesamorelin Nasal Spray

$310.00

Tesamorelin is a synthetic version of the body’s natural growth hormone-releasing hormone (GHRH). In clinical medicine, teamorelin is FDA-approved as an injectable for reducing visceral fat in adults with HIV-related lipodystrophy. 

In research settings, tesamorelin is investigated for:

  • Growth Hormone Pathways: Researchers study how tesamorelin activates growth hormone–releasing pathways, increases IGF-1 levels, and influences downstream signaling in metabolic and endocrine systems.
  • Fat Metabolism & Visceral Fat Regulation: Tesamorelin is being investigated for its effects on fat breakdown, storage, and overall distribution, especially pathways involved in deep abdominal (visceral) fat.
  • Glucose & Insulin Responses: Because tesamorelin affects growth hormone and IGF-1, scientists are exploring how it may influence blood sugar control, insulin sensitivity, and carbohydrate-handling pathways in experimental models.

Our 10 mL Tesamorelin peptide nasal spray contains 20 mg total peptide, releasing a precise 250 mcg amount for research purposes only. Each bottle contains 80 sprays.

Restricted Research Purchase
Purchases are limited to qualified research customers with a verified account. 

  • 99%+ Purity Guaranteed
  • Trusted by Researchers
  • Secure Checkout
⚠️ Notice: This product is for research use only and intended solely for laboratory testing. It is not for human or animal use. Only qualified professionals should handle it. This product is not a drug, food, or cosmetic.
tesamorelin dna structure

What is Tesamorelin?

Tesamorelin is a peptide modeled after GHRH, the hormone that signals the pituitary gland to release growth hormone. It’s clinically used only as an injection, not as a nasal spray. In laboratory research, tesamorelin is studied for its effects on activating growth hormone pathways, influencing fat metabolism, and affecting IGF-1 levels.

The nasal form included here is experimental and intended for studying how tesamorelin behaves via the nasal mucosal route. It is not designed for personal or clinical use.

Tesamorelin Chemical Information

Sequence: Tyr–Ala–Asp–Ala–Ile–Phe–Thr–Asn–Ser–Tyr–Arg–Lys–Leu–Gly–Gln–Leu–Ser–Ala–Arg–Lys–Leu–Leu–Gln–Asp–Ile–Met–Ser–Arg–Gln–Gln–Gly–Glu–Ser–Asn–Gln–Glu–Arg–Gly–Ala–Arg–Ala–Arg–NH₂.
Molecular formula: C221H366N72O67S
Molecular weight: ~5136 g/mol
Form: Synthetic peptide, nasal spray
Other Ingredients: Lab-Grade Distilled Water.

Tesamorelin Nasal Spray  is made with high-purity peptide material and undergoes in-house and third-party lab analysis to confirm:

  • Identify (peptide sequencing verification)
  • Purity (≥99% by HPLC)
  • Absence of contaminants (microbial, heavy metals, solvents)

Lab testing ensures that the material provided is consistent, high-quality, and suitable for research purposes.

Research Related to Tesamorelin

Here are some highlighted studies related to Tesamorelin. Please keep in mind that while these studies are promising, this compound isn’t approved as a drug or dietary supplement in nasal spray form, meaning its use remains limited to research.

Growth Hormone Pathways

Tesamorelin basically “nudges” your own growth hormone system rather than dumping growth hormone from the outside. That means it binds to the same receptor as natural GHRH in the pituitary, triggers GH release in pulses, and then lets IGF‑1 and normal feedback loops do the rest.

Clinical trials in adults (including people with HIV‑related fat gain and people with type 2 diabetes or abdominal obesity) show that daily tesamorelin injections increase growth hormone secretion in a “natural‑like” pulsatile way [1]

Fat Metabolism & Visceral Fat Research

Tesamorelin is best known for helping reduce “deep belly fat” (visceral fat) in people with HIV‑related fat gain, and the research also examines how it alters fat biology and metabolism at a deeper level.

In HIV‑positive adults with significant increases in abdominal fat, daily tesamorelin injections for 6–12 months cut visceral adipose tissue (the fat around organs) by about 15–20% on average compared with placebo [2].

Glucose & Insulin-Related Pathways

Tesamorelin affects glucose and insulin pathways, but the data so far suggest mostly mild, sometimes temporary changes rather than large swings in blood sugar.

In a 12‑week study in people with type 2 diabetes, daily tesamorelin increased IGF‑1 (indicating activation of the growth hormone system) but did not significantly alter overall insulin response or average blood sugar control (HbA1c) [3].

Fasting glucose bumped up slightly early on at higher doses, but this effect faded by week 12, suggesting a transient shift in how the body handles sugar when tesamorelin is first started [3].

Sources

  1. Clemmons, D. R., Miller, S., & Mamputu, J. C. (2017). Safety and metabolic effects of tesamorelin, a growth hormone-releasing factor analogue, in patients with type 2 diabetes: A randomized, placebo-controlled trial. PLoS One, 12(6), e0179538.
  2. Stanley, T. L., Falutz, J., Marsolais, C., Morin, J., Soulban, G., Mamputu, J. C., … & Grinspoon, S. K. (2012). Reduction in visceral adiposity is associated with an improved metabolic profile in HIV-infected patients receiving tesamorelin. Clinical infectious diseases, 54(11), 1642-1651.
  3. Clemmons, D. R., Miller, S., & Mamputu, J. C. (2017). Safety and metabolic effects of tesamorelin, a growth hormone-releasing factor analogue, in patients with type 2 diabetes: A randomized, placebo-controlled trial. PLoS One, 12(6), e0179538.
  4. Makimura, H., Feldpausch, M. N., Rope, A. M., Hemphill, L. C., Torriani, M., Lee, H., & Grinspoon, S. K. (2012). Metabolic effects of a growth hormone-releasing factor in obese subjects with reduced growth hormone secretion: a randomized controlled trial. The Journal of Clinical Endocrinology & Metabolism, 97(12), 4769-4779.
  5. Adrian, S., Scherzinger, A., Sanyal, A., Lake, J. E., Falutz, J., Dubé, M. P., … & Erlandson, K. M. (2019). The growth hormone releasing hormone analogue, tesamorelin, decreases muscle fat and increases muscle area in adults with HIV. The Journal of frailty & aging, 8(3), 154-159.

Frequently asked questions

Can’t find what you need? Contact us and our support team will get back to you within 1–2 business days.

Contact us
What does “For Research Use Only” mean?

All products on Stemcode are intended strictly for laboratory, academic, and scientific research purposes. They are not approved for human or veterinary use.

Due to the sensitive nature of research materials used, all sales are final unless the product arrives damaged or incorrect.

No. Resale or repackaging without authorization is prohibited. Our products are solely for research.

At this moment, we ship only within the United States.

Each product page includes specific storage guidelines (e.g., refrigeration or room temperature).

Restricted Research Access

Age verification is required to enter this site.
You must be greater than 18 years old

This website supplies peptides strictly for laboratory research. By entering this site, you confirm that you are at least 18 years old and understand that these products are sold for research purposes only and not for human or veterinary use. Purchases are restricted to qualified research customers.