Semax
Synthetic Heptapeptide
Semax is a synthetic heptapeptide derived from the ACTH(4-7) fragment with a Pro-Gly-Pro C-terminal extension. Developed at the Institute of Molecular Genetics in Moscow, it has been studied for nootropic and neuroprotective properties.
- BDNF Expression
- Neuroprotection
- Cognitive Function
- Neuroplasticity
Quantified findings reported in the literature
amino acid residues in the Semax heptapeptide sequence
Ashmarin et al., 1995
Published, peer-reviewed studies
A nootropic adrenocorticotropin analog 4-10-semax (15 years experience in its design and study)
View source on PubMed/DOI ↗Semax in prevention of disease progress and development of exacerbations in patients with cerebrovascular insufficiency
View source on PubMed/DOI ↗Semax, an analog of ACTH(4-10) with cognitive effects, regulates BDNF and trkB expression in the rat hippocampus
Study demonstrating Semax-induced upregulation of BDNF and its receptor TrkB in rat hippocampus and cortex, supporting neuroprotective mechanisms.
View source on PubMed/DOI ↗
Third-party analytical reports
Certificates of Analysis from independent laboratories for products supplied by Stemcode. Reported values describe the analysed material; they are reported as documented and are distinct from the published literature above.
- Net content
- 11.3 mg
- Lot
- SP26-SMV10
- COA #
- COA-2026-9149580
- Report date
- 07/17/2026
- Net content
- 33 mg
- Lot
- SP26-SMN30
- COA #
- COA-2026-9149598
- Report date
- 07/17/2026
Stemcode supplies Semax as a research-grade compound for laboratory research use only — not for human or animal consumption.
View the research-grade product →