high fragmant 176-191

Hgh-Fragment 176-191 Nasal Spray

$89.00

hGH-Fragment is a synthetic peptide fragment from the C-terminal region of human growth hormone (hGH). What makes this fragment unique from the full hGH sequence is that it’s used in studies for its selective interaction with fat-metabolism signaling pathways without fully engaging the growth-promoting actions of the hormone.

In research settings, hGH Fragment 176–191 is studied for: 

  • Fat Loss: Researchers are investigating how hGH Fragment 176–191 targets adipose tissue, stimulates lipolysis (the breakdown of stored triglycerides into free fatty acids and glycerol), and inhibits lipogenesis (the creation of new fat), which may help with body recomposition goals. 
  • Comparative Research & Analogue Development: Scientists studied Fragment 176-191 to develop the analogue AOD-9604, which is primarily studied for its effects on fat signalling pathways.

Our hGH Fragment 176–191 Nasal Spray is formulated for laboratory and investigative research, offering a convenient delivery format for precise experimental work. Each container contains 10 mL of a solution with 5 mg of pure hGH Fragment 176–191 and approximately 80 sprays.

Please note that all payments include a 3.99% processing fee set by our international payment processor.

⚠️ Notice: This product is for research use only and intended solely for laboratory testing. It is not for human or animal use. Only qualified professionals should handle it. This product is not a drug, food, or cosmetic.

What is hGH-Fragment 176-191?

hGH Fragment 176-191 is a short peptide segment of amino acids 176 through 191 of human growth hormone (hGH). Researchers are interested in this portion of hGH for its potential for fat loss without inducing the endocrine effects of full-length hGH. 

hGH is not the same as AOD-9604, which is a modified analogue that has been more extensively studied. They’re often grouped together, but Fragment 176-191 is the native C-terminal fragment and was the blueprint for analogue development for more stable molecules.

hGH-Fragment 176-191 Peptide Chemical Information

Sequence: H‑Tyr‑Leu‑Arg‑Ile‑Val‑Gln‑Cys‑Arg‑Ser‑Val‑Glu‑Gly‑Ser‑Cys‑Gly‑Phe‑OH
Molecular formula: C₇₈H₁₂₅N₂₃O₂₃S₂
Molecular weight: ~1817.1 g/mol
Form: Synthetic peptide, nasal spray research solution
Other Ingredients: Lab-Grade Distilled Water.

Each batch of our hGH-Fragment 176-191 nasal spray is made using high-purity synthetic peptide material and undergoes internal and third-party lab analysis to verify: 

  • Identify (peptide sequencing verification)
  • Purity (≥99% by HPLC)
  • Absence of contaminants (microbial, heavy metals, solvents)

All materials are supplied strictly for research and laboratory use only. 

Research Related to hGH Fragment 176-191 Peptide

hGH Fragment 176-191 is primarily studied in the lab and in comparative research, where scientists examine how this specific region of human growth hormone might influence fat-related signaling and serve as a blueprint for modified analogs such as AOD-9604. 

Analogue Development

Fragment 176-191 was used as a template after researchers realized that the C-terminus of hGH carried most of the fat-specific actions, and was then systematically modified to yield AOD-9604 and other analogues [1]. 

Fat Loss and Metabolism

hGH Fragment 176-191 is found to act as lipolytic/antilipogenic, which means it stimulates the breakdown of triglycerides and suppresses new fat from forming. Unlike the full-length hGH, the C-terminal fragment doesn’t activate the growth hormone receptor or interfere with insulin secretion [1, 2]. 

Sources

  1. Heffernan, M., Summers, R. J., Thorburn, A., Ogru, E., Gianello, R., Jiang, W. J., & Ng, F. M. (2001). The Effects of Human GH and Its Lipolytic Fragment (AOD9604) on Lipid Metabolism Following Chronic Treatment in Obese Mice andβ 3-AR Knock-Out Mice. Endocrinology, 142(12), 5182-5189.
  2. Heffernan, M. A., Thorburn, A. W., Fam, B., Summers, R., Conway-Campbell, B., Waters, M. J., & Ng, F. M. (2001). Increase of fat oxidation and weight loss in obese mice caused by chronic treatment with human growth hormone or a modified C-terminal fragment. International journal of obesity, 25(10), 1442-1449.

Frequently asked questions

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What does “For Research Use Only” mean?

All products on Stemcode are intended strictly for laboratory, academic, and scientific research purposes. They are not approved for human or veterinary use.

Due to the sensitive nature of research materials used, all sales are final unless the product arrives damaged or incorrect.

No. Resale or repackaging without authorization is prohibited. Our products are solely for research.

At this moment, we ship only within the United States.

Each product page includes specific storage guidelines (e.g., refrigeration or room temperature).

Description

hGH-Fragment is a synthetic peptide fragment from the C-terminal region of human growth hormone (hGH). What makes this fragment unique from the full hGH sequence is that it’s used in studies for its selective interaction with fat-metabolism signaling pathways without fully engaging the growth-promoting actions of the hormone.

Additional information

Weight 0.01875 lbs

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